Radiation Injury of the Rectum

Radiation-induced carcinoma of the rectum.

Carcinomas and sarcomas are known to develop after radiation therapy. A complete review of the literature regarding appearance of carcinoma of the rectum following radiation therapy to the pelvis was undertaken. The average interval between irradiation and diagnosis of the rectal cancer was 15.2 years, the range being from one year, two months to 33 years. We present a case of carcinoma of the ...

Radiation-induced leiomyosarcoma of the rectum after cervical cancer treatment.

The effects of volumetric changes on radiation doses of the rectum and bladder during radiotherapy in patients with prostate cancer

Background: In prostate radiotherapy, changes in the volume of the bladder and rectum can influence dose delivery. In this study, cone-beam computerised tomography (CBCT) imaging was used to assess volumetric, and corresponding radiation dosimetric changes, for the bladder and rectum in patients with prostate cancer treated using VMAT. Materials and Methods: Treatment planning computed tomograp...

The Evaluation of Melatonin Effect Against The Early Effect of Ionizing Radiation Induced Lung Injury

Background & Objective: Lung is a radiosensitive organ. Patients who are undergoing radiation therapy in their chest are subjected to radiation pneumonitis in the early phase and pulmonary fibrosis in the late one. Melatonin scavenges free radicals directly and acts as an indirect antioxidant through the activation of major antioxidant enzymes as well. The aim of the study thus is to investiga...

Establishment of a rat model of radiation-induced lung injury

Background: Radiation-induced lung injury is a refractory side effect in lung cancer radiotherapy, the mechanism still remains unclear, hence an appropriate animal mode may become useful to investigate it. Materials and Methods: 50 female Wistar rats were randomly divided into 5 groups, average 10 rats/cage: A. control group B. 3Gy×10f C. 6Gy×5f D. 12.5Gy×1f E.15.3Gy×1f....